Irf7 mouse
WebJul 7, 2024 · It remains possible that IRF7, a homolog of IRF3, compensates for the loss of IRF3 and explains the IRF3-independent resistance to HSV-1 that we observe. ... Mouse primary microglia cells and ... WebProduct Details. Partial mouse IRF7 recombinant protein (127-487a.a.) expressed in E. coli. Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. The antibody was purified by affinity chromatography. The antibody solution should be stored undiluted between 2°C and 8°C.
Irf7 mouse
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WebNov 30, 2024 · IRF7 could regulate the transcription of Usp25 in mouse embryonic fibroblast (MEFs) and BM-derived dendritic cells (BMDCs) in response to viral infection or LPS. 42 It was reported that Usp25 binds with the promoter of Sox2 that played an important role in the pluripotency of embryonic stem cells development. 43, 44 Whether Usp25 is a potential ... WebRestoration of IRF7 in tumor cells isolated from metastatic mouse primary mammary tumors restored the ability to secrete IFN and reduced the metastatic burden in a breast cancer tumor mouse model [165]. Decreased IRF7 expression levels were found to correlate with increased metastatic events in human breast cancer, supporting the notion that ...
IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including the type I interferon genes. In particular, IRF7 regulates many interferon-alpha genes. Constitutive expression of IRF7 is largely restricted to lymphoid tissue, largely plasmacytoid dendritic cells, whereas IRF7 is inducible in many tissues. Multiple IRF7 tra… WebIRF7 Antibodies Antibodies that detect IRF7 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Flow Cytometry, Immunocytochemistry …
WebInterferon regulatory factor 7 (IRF7) is the main transcriptional regulator of type I IFN, and it is crucial for the induction of IFNα/β and the type I IFN-dependent immune response. In this study, we focused on the role of IRF7 in the pathogenicity and immunogenicity of RABV using an IRF7 -/- mouse model. WebIn this study, we analyzed the role of IRF3 and IRF7 for the host response to IAV infections in Irf3-/-, Irf7-/-, and Irf3-/-Irf7-/- knockout mice. While the absence of IRF3 had only a …
WebAug 21, 2024 · IRF-7 Antibody (G-8): sc-74472 IRF-7 Antibody (G-8) is a mouse monoclonal IgG 2a κ IRF-7 antibody, cited in 26 publications, provided at 200... IRF-7 Antibody (G-8) is …
WebPhospho-IRF-7 (Ser437/438) (D6M2I) Rabbit mAb (Mouse Specific) recognizes endogenous levels of mouse IRF-7 protein when dually phosphorylated at Ser437 and Ser438. This … onpoint credit union newsWebInterferon regulatory receptor 7 (IRF7) is a transcription factor involved in the activation of the type I interferon (IFN) response upon pathogenic infection [3-4]. IRF7 has been implicated downstream of several pattern recognition receptors (PRRs), including TLRs, RLRs, and DNA sensors [2]. inx dividend historyWebJun 19, 2024 · To elucidate pDC immunomodulatory functions, we developed a mouse model in which IRF7 signaling is restricted to pDC. Despite undetectable levels of IFN-I protein, pDC-restricted IRF7 signaling controlled both viruses and was sufficient to protect mice from lethal CHIKV infection. Early pDC IRF7-signaling resulted in amplification of … inxcy.comWebRestoration of IRF7 in tumor cells isolated from metastatic mouse primary mammary tumors restored the ability to secrete IFN and reduced the metastatic burden in a breast … onpoint credit union near me numberWebApr 12, 2024 · IRF7 suppresses hematopoietic regeneration under stress via CXCR4. The role of interferon regulatory factor 7 in the pathogenicity and immunogenicity of rabies … in x-directiononpoint credit union order checksWebImmunohistochemistry (Paraffin) analysis of IRF7 in paraffin-embedded mouse heart tissue. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes.The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with IRF7 Recombinant ... onpoint credit union mall 205 portland oregon