WebbColumn: MAbPac SEC-1, 5 µm, Dimension: a. 4.0 × 300 mm × 150 mm Mobile phase: 50mM Sodium Phosphate pH 6.8, in 300 mM NaCl Temp.: 30 ºC Flow rate: 200 µL/min Inj. volume: 2 µL Detection: 280 nm Sample: mAb (5 mg/mL) (a) 4.0 × 300 mm (b) 4.0 × 150 mm Aggregates 13 Ion exchange protein columns – charge variants 10 µm Nonporous WebbThermo Scientific™MAbPac HIC-Butyl 5µm, 4.6 × 100 mm column Product code: 088558 • Antibody drug conjugates (ADC) require extended characterization to determine the amount of drug attached to monoclonal antibody due to potency of attached drug • Confirmation of Drug to Antibody Ratio (DAR) for ADC • Stable at wide pH range 2-12
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WebbAplicaciones. La columna Thermo Scientific™ MAbPac HIC-10 es la columna a elegir para mAb’s/proteínas intactas y agregados mAb’s, mientras que MAbPac HIC-20 es adecuada para resolver fragmentos de mAb’s, mAb’s oxidados y mAb’s biespecíficos. Para Conjugados de Drogas con mAb’s (ADC’s) MAbPac HIC-Butyl resulta ideal para ADC ... Webb25 okt. 2016 · RP conditions: MabPac HIC-10 100 mm × 4.6 mm column, mobile phase “A”: 2 M ammonium-sulfate + 0.1 M phosphate (pH = 7), mobile phase “B”: 0.1 M phosphate (pH = 7), 0–100% B gradient in 10 min, flow rate: 1 mL/min, temperature: 25 … malls in west des moines ia
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WebbColumn: MAbPac HIC-Butyl, 5 µm Format: 4.6 ×100 mm (P/N 088558) Mobile 1.5 M ammonium sulfate, 50 mM sodium phase A: phosphate, pH 7.0 / isopropanol (95:5 v/v) Mobile 50 mM sodium phosphate, phase B: pH 7.0 / isopropanol (80:20 v/v) Gradient: Time (min) %A %B -6.0 80 20 0.0 80 20 1.0 80 20 21.0 60 40 21.2 0 100 24.0 0 100 Flow rate: … Webb14 apr. 2024 · 『MAbPac HIC-Butylカラム』は、ポリマー基材の高分離疎水相互作用 クロマトグラフィー（HIC）カラムです。 特にmAbやADC（antibody-drug conjugates:抗体 … WebbMAbPac HIC-10, 5 µm, 4.6 × 100 mm (P/N 088480) MAbPac HIC-20, 5 µm, 4.6 × 100 mm (P/N 088553) MAbPac 140HIC-20, 5 µm, 4.6 × 250 mm (P/N 088554) MAbPac HIC-Butyl, … malls in zamboanga city